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The skin cell gun, also known as the skin gun or SkinGun, is a medical device that sprays a patient's own self-donated (autologous) stem cells to treat burns and other wounds. The skin gun is used in conjunction with a technique that isolates adult stem cells from a postage stamp-sized sample of the patient's own skin for application to the wound site, where they differentiate into normal skin. This treatment can replace conventional methods of treating severe wounds, such as skin grafting. Studies demonstrate that damaged skin tissue regenerates after skin gun treatment significantly more quickly than after traditional treatment methods. 〔Hartmann B., et al. (Sprayed cultured epithelial autografts for deep dermal burns of the face and neck ). Ann Plast Surg. 2007 Jan;58(1):70-3. (link retrieved Feb 4, 2015)〕 〔Gerlach, J. C. et al. (Method for autologous single skin cell isolation for regenerative cell spray transplantation with non-cultured cells ). Int J Artif Organs 2011; 34(3): 271 - 279 (link retrieved Feb 4, 2015)〕 〔Gerlach, J. C. et al. (Autologous skin cell spray-transplantation for a deep dermal burn patient in an ambulant treatment room setting ). Burns 37, e19-e23 (2011) (link retrieved Feb 4, 2015)〕 The skin gun, along with related cell isolation methodologies, were acquired by RenovaCare, Inc. in 2013.〔(RenovaCare, Inc. (formerly Janus Resources, Inc.) SEC form 8-K/A filed on November 21, 2013. ). (link retrieved Feb 4, 2015)〕 The company continues to develop the technology and treatment protocol for commercial distribution, under the brand names SkinGun and CellMist System respectively. RenovaCare is also exploring opportunities to apply its SkinGun treatments to additional indications, including chronic wounds, pigmentation disorders, and cosmetic applications. 〔(RenovaCare, Inc. Website Technology Q&A ) (link retrieved Feb 4, 2015)〕 ==Operation== Stem cells from a postage stamp-sized sample of the patient's healthy skin are isolated using a enzymatic tissue processing protocol. The resulting cell suspension is then transferred to a sterile syringe, which is then inserted into the skin gun. Using its unique spray mechanism, the gun uniformly distributes cells directly into the wound. The newly introduced stem cells begin to migrate, multiply, and differentiate, creating new skin tissue in a matter of days. The entire process – from collecting the skin sample, processing it into a cell suspension, and using the skin gun to spray the stem cells – takes approximately 1.5–2 hours from start to finish. Full re-epithelialization can occur in as little as four days, and after a few months the skin will regain its color and texture.〔Lorianna De Giorgio, ("Skin gun that sprays stem cells being used on burn victims" ), ''Toronto Star'', February 7, 2011〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Skin cell gun」の詳細全文を読む スポンサード リンク
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